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Amoxicillin prescription required for penicillin allergy after 2 months of treatment.4 Therefore, it is not surprising that the efficacy was only 30% after 1 month and 56% 7 days without treatment. The efficacy can be better for 2 or 3-month-old infants but still not reached in our study. The number of patients with severe complications and the duration of their hospital stay was lower in the treated group (P <.001). In the subgroup analysis, no differences were found in complications, duration of hospital stay and mortality. In our cohort, 1 case of pneumothorax was registered, which an early and rare complication. Only one (2%) of the patients had to be admitted the hospital, and both patients survived with good clinical outcome. A previous publication1 reported that after 1 month of antibiotics, approximately 20% patients had to be admitted the hospital for pneumothorax, and 2, 3 years later, 30% of these patients had to undergo pneumo-intensive care unit (PICU) admission. The number of patients who developed pneumo-encephalopathy is low because the number of pneumothorax patients was small. However, a few of these patients had neurologic and pulmonary symptoms. In this study, no patients had a subsequent pulmonary complications after 1 year of treatment. However, our study does not allow for a direct causal analysis. We assume that the pneumonia developed only as a result of antibiotic-associated can i buy amoxicillin over the counter in uk diarrhea and that antibiotic withdrawal caused this complication. In our study and similar reports, the number severity of other complications were similar. Pneumonia can be a complication of penicillin allergy,1 which can explain the low efficacy rate. Another reason for the findings of this study is the lack of information about mechanism pneumonia caused by the pneumococci in penicillin allergy. It is well known that bacterial pneumonia is caused by a toxin that initiates nephritis, necrotizing fasciitis, and disseminated intravascular coagulation.5-7 Infection of the lung with other bacterial species results in development of pneumococcal pneumonia; there is almost 100% mortality. Moreover, infections caused by different species of cheap drugstore matte lipstick bacteria can also lead to disseminated disease and proteinuria.8-10 These pathogens produce different extracellular toxins, and it has been suggested that they may be important for pneumococcal pneumonia.11 The pathogenicity of strains pneumococci used in our study did not indicate a difference in potency between the 2 groups of pneumococci. lack a change in the potency by decreasing dosage of penicillin or other related antibiotics cannot explain this finding. In a previous study,6 we found that most strains were antibiotic resistant or susceptible to some antibiotics, which could be the possible cause of lack effect antibiotics in the 2 groups. Moreover, we found that most strains were resistant to the second generation cephalosporins.13 Although we can only speculate, one hypothesis might be that these strains have acquired mutations that would make them resistant to antibiotics;
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